RNA Details
Disease Name
myocardial infarction
Tissue
heart
RNA Symbol
mir-144
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
hydroxyproline; post picosirius red staining; Echocardiography etc.
Target
ZEB1;LOX1
Pathway
NA
PubMed ID
Title
Loss of miR-144 signaling interrupts extracellular matrix remodeling after myocardial infarction leading to worsened cardiac function
Year
2018
Function
miR-144 is involved in extracellular matrix remodeling post myocardial infarction (MI) and its loss leads to increased myocardial fibrosis and impaired functional recovery.